PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze
Rhinovirus (RV) infections can trigger acute exacerbations of respiratory diseases. Here, Niespodziana et al. develop a PreDicta chip that identifies the culprit RV strain from small blood samples and show that RV-A and RV-C strains are associated with most severe symptoms.
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| Language: | English |
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Nature Publishing Group
2018-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-04591-0 |
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doaj-f0e5b1e0483a415e8d8be627de283b8b2021-05-11T09:36:25ZengNature Publishing GroupNature Communications2041-17232018-06-019111110.1038/s41467-018-04591-0PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheezeKatarzyna Niespodziana0Katarina Stenberg-Hammar1Spyridon Megremis2Clarissa R. Cabauatan3Kamila Napora-Wijata4Phyllis C. Vacal5Daniela Gallerano6Christian Lupinek7Daniel Ebner8Thomas Schlederer9Christian Harwanegg10Cilla Söderhäll11Marianne van Hage12Gunilla Hedlin13Nikolaos G. Papadopoulos14Rudolf Valenta15Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of ViennaAstrid Lindgren Children’s Hospital, Karolinska University HospitalDivision of Infection, Immunity & Respiratory Medicine, University of ManchesterDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of ViennaDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of ViennaDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of ViennaDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of ViennaDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of ViennaPhadia Austria GmbH, Part of Thermo Fisher Scientific ImmunoDiagnosticsPhadia Austria GmbH, Part of Thermo Fisher Scientific ImmunoDiagnosticsPhadia Austria GmbH, Part of Thermo Fisher Scientific ImmunoDiagnosticsDepartment of Women’s and Children’s Health, Karolinska InstitutetImmunology and Allergy Unit, Department of Medicine Solna, Karolinska Institutet and University HospitalAstrid Lindgren Children’s Hospital, Karolinska University HospitalDivision of Infection, Immunity & Respiratory Medicine, University of ManchesterDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of ViennaRhinovirus (RV) infections can trigger acute exacerbations of respiratory diseases. Here, Niespodziana et al. develop a PreDicta chip that identifies the culprit RV strain from small blood samples and show that RV-A and RV-C strains are associated with most severe symptoms.https://doi.org/10.1038/s41467-018-04591-0 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Katarzyna Niespodziana Katarina Stenberg-Hammar Spyridon Megremis Clarissa R. Cabauatan Kamila Napora-Wijata Phyllis C. Vacal Daniela Gallerano Christian Lupinek Daniel Ebner Thomas Schlederer Christian Harwanegg Cilla Söderhäll Marianne van Hage Gunilla Hedlin Nikolaos G. Papadopoulos Rudolf Valenta |
| spellingShingle |
Katarzyna Niespodziana Katarina Stenberg-Hammar Spyridon Megremis Clarissa R. Cabauatan Kamila Napora-Wijata Phyllis C. Vacal Daniela Gallerano Christian Lupinek Daniel Ebner Thomas Schlederer Christian Harwanegg Cilla Söderhäll Marianne van Hage Gunilla Hedlin Nikolaos G. Papadopoulos Rudolf Valenta PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze Nature Communications |
| author_facet |
Katarzyna Niespodziana Katarina Stenberg-Hammar Spyridon Megremis Clarissa R. Cabauatan Kamila Napora-Wijata Phyllis C. Vacal Daniela Gallerano Christian Lupinek Daniel Ebner Thomas Schlederer Christian Harwanegg Cilla Söderhäll Marianne van Hage Gunilla Hedlin Nikolaos G. Papadopoulos Rudolf Valenta |
| author_sort |
Katarzyna Niespodziana |
| title |
PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze |
| title_short |
PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze |
| title_full |
PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze |
| title_fullStr |
PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze |
| title_full_unstemmed |
PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze |
| title_sort |
predicta chip-based high resolution diagnosis of rhinovirus-induced wheeze |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2018-06-01 |
| description |
Rhinovirus (RV) infections can trigger acute exacerbations of respiratory diseases. Here, Niespodziana et al. develop a PreDicta chip that identifies the culprit RV strain from small blood samples and show that RV-A and RV-C strains are associated with most severe symptoms. |
| url |
https://doi.org/10.1038/s41467-018-04591-0 |
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