Statins Reduce Lipopolysaccharide-Induced Cytokine and Inflammatory Mediator Release in an In Vitro Model of Microglial-Like Cells
The anti-inflammatory effects of statins (HMG-CoA reductase inhibitors) within the cardiovascular system are well-established; however, their neuroinflammatory potential is unclear. It is currently unknown whether statins’ neurological effects are lipid-dependent or due to pleiotropic mechanisms. Th...
Main Authors: | A. J. McFarland, A. K. Davey, S. Anoopkumar-Dukie |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2017/2582745 |
Similar Items
-
Molecular Mechanisms Underlying the Effects of Statins in the Central Nervous System
by: Amelia J. McFarland, et al.
Published: (2014-11-01) -
SIRT1 and SIRT2 Modulators: Potential Anti-Inflammatory Treatment for Depression?
by: Yuqing Zhang, et al.
Published: (2021-02-01) -
Anti-inflammatory homoeopathic drug dilutions restrain lipopolysaccharide-induced release of pro-inflammatory cytokines: In vitro and in vivo evidence
by: Umesh B Mahajan, et al.
Published: (2017-01-01) -
Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury
by: Ulrich Goebel, et al.
Published: (2021-01-01) -
Vitamin D3 and Suppressor of Cytokine Signaling Proteins Reduces Pro-Inflammatory Cytokines in an Alzheimer’s Disease Like-Model Consisting of Microglial and Neuronal Co-Cultures
by: Evdokiou, Alexander
Published: (2017)