Neonatal androgenization exacerbates alcohol-induced liver injury in adult rats, an effect abrogated by estrogen.
Alcoholic liver disease (ALD) affects millions of people worldwide and is a major cause of morbidity and mortality. However, fewer than 10% of heavy drinkers progress to later stages of injury, suggesting other factors in ALD development, including environmental exposures and genetics. Females displ...
Main Authors: | Whitney M Ellefson, Ashley M Lakner, Alicia Hamilton, Iain H McKillop, Herbert L Bonkovsky, Nury M Steuerwald, Yvette M Huet, Laura W Schrum |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3243688?pdf=render |
Similar Items
-
Arsenic abrogates the estrogen-signaling pathway in the rat uterus
by: Chatterji Urmi, et al.
Published: (2010-07-01) -
Antioxidants Abrogate Alpha-Tocopherylquinone-Mediated Down-Regulation of the Androgen Receptor in Androgen-Responsive Prostate Cancer Cells.
by: Alexandra M Fajardo, et al.
Published: (2016-01-01) -
Hormones and prostate carcinogenesis: Androgens and estrogens
by: Maarten C Bosland, et al.
Published: (2011-01-01) -
The insulin-like growth factor-I-nitric oxide axis : a study in the isolated perfused rat kidney
by: McKillop, Iain Hugh
Published: (1995) -
Androgens and estrogens in skeletal sexual dimorphism
by: Michaël Laurent, et al.
Published: (2014-04-01)