Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia

The aim of this study was to determine how different types of P. vivax affect clinical symptoms and parasitaemia clearance. Blood was collected from individuals from Pará State, Brazil. The patients were treated as chloroquine plus primaquine. P. vivax were typed daily till D7 and again on D30. Now...

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Main Authors: Ricardo Luiz Dantas Machado, Alberto Ferreira de Figueiredo Filho, Vanja Sueli Pachiano Calvosa, Maria Cristina Figueredo, José Maria Nascimento, Marinete Marins Póvoa
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300002&lng=en&tlng=en
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spelling doaj-f0d70edf6d1c4d2f96e3b5b9536f5ab12020-11-25T03:24:41ZengElsevierBrazilian Journal of Infectious Diseases1678-43917317517710.1590/S1413-86702003000300002S1413-86702003000300002Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemiaRicardo Luiz Dantas MachadoAlberto Ferreira de Figueiredo FilhoVanja Sueli Pachiano CalvosaMaria Cristina FigueredoJosé Maria NascimentoMarinete Marins PóvoaThe aim of this study was to determine how different types of P. vivax affect clinical symptoms and parasitaemia clearance. Blood was collected from individuals from Pará State, Brazil. The patients were treated as chloroquine plus primaquine. P. vivax were typed daily till D7 and again on D30. Now we can confirm a previously reported correlation between P. vivax genotype and response to chloroquine. Clinical symptoms do not allow for objective identification of different P. vivax types in the Brazilian Amazon, since the VK247 and P. vivax-like have only been detected in mixed infections.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300002&lng=en&tlng=enPlasmodium vivax variantssymptomschloroquine and primaquine treatmentclearence of parasitaemia
collection DOAJ
language English
format Article
sources DOAJ
author Ricardo Luiz Dantas Machado
Alberto Ferreira de Figueiredo Filho
Vanja Sueli Pachiano Calvosa
Maria Cristina Figueredo
José Maria Nascimento
Marinete Marins Póvoa
spellingShingle Ricardo Luiz Dantas Machado
Alberto Ferreira de Figueiredo Filho
Vanja Sueli Pachiano Calvosa
Maria Cristina Figueredo
José Maria Nascimento
Marinete Marins Póvoa
Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia
Brazilian Journal of Infectious Diseases
Plasmodium vivax variants
symptoms
chloroquine and primaquine treatment
clearence of parasitaemia
author_facet Ricardo Luiz Dantas Machado
Alberto Ferreira de Figueiredo Filho
Vanja Sueli Pachiano Calvosa
Maria Cristina Figueredo
José Maria Nascimento
Marinete Marins Póvoa
author_sort Ricardo Luiz Dantas Machado
title Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia
title_short Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia
title_full Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia
title_fullStr Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia
title_full_unstemmed Correlation between Plasmodium vivax variants in Belém, Pará State, Brazil and symptoms and clearance of parasitaemia
title_sort correlation between plasmodium vivax variants in belém, pará state, brazil and symptoms and clearance of parasitaemia
publisher Elsevier
series Brazilian Journal of Infectious Diseases
issn 1678-4391
description The aim of this study was to determine how different types of P. vivax affect clinical symptoms and parasitaemia clearance. Blood was collected from individuals from Pará State, Brazil. The patients were treated as chloroquine plus primaquine. P. vivax were typed daily till D7 and again on D30. Now we can confirm a previously reported correlation between P. vivax genotype and response to chloroquine. Clinical symptoms do not allow for objective identification of different P. vivax types in the Brazilian Amazon, since the VK247 and P. vivax-like have only been detected in mixed infections.
topic Plasmodium vivax variants
symptoms
chloroquine and primaquine treatment
clearence of parasitaemia
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300002&lng=en&tlng=en
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