Links between copper and cholesterol in Alzheimer’s disease

Links between copper and cholesterol in Alzheimer’s disease

Altered copper homeostasis and hypercholesterolemia have been identified independently as risk factors for Alzheimer’s disease (AD). Abnormal copper and cholesterol metabolism are implicated in the genesis of amyloid plaques and neurofibrillary tangles (NFT), which are two key pathological signatur...

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Bibliographic Details
Main Authors:	Ya Hui eHung, Ashley I. Bush, Sharon eLa Fontaine
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2013-05-01
Series:	Frontiers in Physiology
Subjects:	Cholesterol Copper lipid rafts Alzheimer’s disease amyloid precursor protein tau
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00111/full

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