Depletion of β3-adrenergic receptor relieves pressure overload-induced cardiac hypertrophy and heart failure via enhancing innate immune response

Depletion of β3-adrenergic receptor relieves pressure overload-induced cardiac hypertrophy and heart failure via enhancing innate immune response

Cardiac pressure overload is a crucial risk factor for cardiac hypertrophy and heart failure. Our previous study showed that depletion of the β3-adrenergic receptor (ADRB3) induced left ventricular diastolic dysfunction via potential regulation of energy metabolism and cardiac contraction. However,...

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Bibliographic Details
Main Authors: Xuemei Wei, Andi Zhang, Wenbo Yang, Yuehua Fang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
β3-adrenergic receptor
Heart failure
Cardiac hypertrophy
Innate immune response
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221009781

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