Depressive symptoms in Crohn's disease: relationship with immune activation and tryptophan availability.

Depressive symptoms in Crohn's disease: relationship with immune activation and tryptophan availability.

Crohn's disease (CD) is associated with immune activation and depressive symptoms. This study determines the impact of anti-tumor necrosis factor (TNF)-α treatment in CD patients on depressive symptoms and the degree to which tryptophan (TRP) availability and immune markers mediate this effect....

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Bibliographic Details
Main Authors:	Sinan Guloksuz, Marieke Wichers, Gunter Kenis, Maurice G V M Russel, Annick Wauters, Robert Verkerk, Baer Arts, Jim van Os
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3609785?pdf=render

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