Recombinant Adenovirus KGHV500 and CIK Cells Codeliver Anti-p21-Ras scFv for the Treatment of Gastric Cancer with Wild-Type Ras Overexpression

Recombinant Adenovirus KGHV500 and CIK Cells Codeliver Anti-p21-Ras scFv for the Treatment of Gastric Cancer with Wild-Type Ras Overexpression

The development of gastric cancer is frequently related to the overexpression of wild-type p21 proteins, but it is rarely related to mutated Ras proteins. We previously constructed a broad-spectrum anti-p21-Ras single-chain variable fragment antibody (scFv), which was carried by the oncolytic adenov...

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Bibliographic Details
Main Authors:	Mingjuan Wang, Yanling Hong, Qiang Feng, Xinyan Pan, Shuling Song, Jing Cui, Jin Lei, Hong Fang, Julun Yang
Format:	Article
Language:	English
Published:	Elsevier 2018-12-01
Series:	Molecular Therapy: Oncolytics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2372770518300275

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