Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts

Mango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance to ginger but imparts raw mango flavour. The sequential extraction of mango ginger rhizome powder was carried out using hexane, chloroform, ethyl acetate, acetone, methanol and water. The phenolic content was the h...

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Main Authors: Raghu H. Chandrashekhar, Somaradhya M. Aradhya, Lokendra Singh, Rudragoud S. Policegoudra
Format: Article
Language:English
Published: University of Zagreb 2011-01-01
Series:Food Technology and Biotechnology
Subjects:
Online Access:http://hrcak.srce.hr/file/103514
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spelling doaj-f0b5025e592a458492a2a9efb839ef872020-11-25T01:37:46ZengUniversity of ZagrebFood Technology and Biotechnology1330-98621334-26062011-01-01492162168Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. ExtractsRaghu H. Chandrashekhar0Somaradhya M. Aradhya1Lokendra Singh2Rudragoud S. Policegoudra3Manipal College of Pharmaceutical Sciences, Manipal University, 576104 Manipal, Karnataka, IndiaCentral Food Technological Research Institute, 570020 Mysore, Karnataka, IndiaDefence Research Laboratory, 784001 Tezpur, Assam, IndiaDefence Research Laboratory, 784001 Tezpur, Assam, IndiaMango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance to ginger but imparts raw mango flavour. The sequential extraction of mango ginger rhizome powder was carried out using hexane, chloroform, ethyl acetate, acetone, methanol and water. The phenolic content was the highest in methanol extract, followed by acetone, ethyl acetate and water extracts. Among these, chloroform extract exhibited high lipid peroxidation inhibitory activity and metal chelating activity, whereas ethyl acetate extract showed high DPPH radical scavenging activity and superoxide radical scavenging activity. Mango ginger extracts also showed potential platelet aggregation inhibitory activity and cytotoxicity properties.http://hrcak.srce.hr/file/103514Curcuma amadamango gingerantioxidant activityphenolicsplatelet aggregation inhibitory activitycytotoxicity
collection DOAJ
language English
format Article
sources DOAJ
author Raghu H. Chandrashekhar
Somaradhya M. Aradhya
Lokendra Singh
Rudragoud S. Policegoudra
spellingShingle Raghu H. Chandrashekhar
Somaradhya M. Aradhya
Lokendra Singh
Rudragoud S. Policegoudra
Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts
Food Technology and Biotechnology
Curcuma amada
mango ginger
antioxidant activity
phenolics
platelet aggregation inhibitory activity
cytotoxicity
author_facet Raghu H. Chandrashekhar
Somaradhya M. Aradhya
Lokendra Singh
Rudragoud S. Policegoudra
author_sort Raghu H. Chandrashekhar
title Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts
title_short Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts
title_full Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts
title_fullStr Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts
title_full_unstemmed Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts
title_sort cytotoxicity, platelet aggregation inhibitory and antioxidant activity of curcuma amada roxb. extracts
publisher University of Zagreb
series Food Technology and Biotechnology
issn 1330-9862
1334-2606
publishDate 2011-01-01
description Mango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance to ginger but imparts raw mango flavour. The sequential extraction of mango ginger rhizome powder was carried out using hexane, chloroform, ethyl acetate, acetone, methanol and water. The phenolic content was the highest in methanol extract, followed by acetone, ethyl acetate and water extracts. Among these, chloroform extract exhibited high lipid peroxidation inhibitory activity and metal chelating activity, whereas ethyl acetate extract showed high DPPH radical scavenging activity and superoxide radical scavenging activity. Mango ginger extracts also showed potential platelet aggregation inhibitory activity and cytotoxicity properties.
topic Curcuma amada
mango ginger
antioxidant activity
phenolics
platelet aggregation inhibitory activity
cytotoxicity
url http://hrcak.srce.hr/file/103514
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AT lokendrasingh cytotoxicityplateletaggregationinhibitoryandantioxidantactivityofcurcumaamadaroxbextracts
AT rudragoudspolicegoudra cytotoxicityplateletaggregationinhibitoryandantioxidantactivityofcurcumaamadaroxbextracts
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