Functional Magnetic Core-Shell System-Based Iron Oxide Nanoparticle Coated with Biocompatible Copolymer for Anticancer Drug Delivery

Functional Magnetic Core-Shell System-Based Iron Oxide Nanoparticle Coated with Biocompatible Copolymer for Anticancer Drug Delivery

Polymer coating has drawn increasing attention as a leading strategy to overcome the drawbacks of superparamagnetic iron oxide nanoparticles (SPIONs) in targeted delivery of anticancer drugs. In this study, SPIONs were modified with heparin-Poloxamer (HP) shell to form a SPION@HP core-shell system f...

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Bibliographic Details
Main Authors: Thai Thanh Hoang Thi, Diem-Huong Nguyen Tran, Long Giang Bach, Hieu Vu-Quang, Duy Chinh Nguyen, Ki Dong Park, Dai Hai Nguyen
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Pharmaceutics
Subjects:
iron oxide nanoparticles
core-shell structure
surface modification
Poloxamer
heparin
doxorubicin
Online Access:http://www.mdpi.com/1999-4923/11/3/120

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