Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers

Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers

BACKGROUND: Although centrilobular emphysema, and small airway, interstitial and alveoli inflammation can be detected pathologically in the lungs of smokers with relatively well preserved lung function, these changes are difficult to assess using available physiological tests. Because submaximal sin...

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Main Authors: DJ Cotton, JT Mink, BL Graham
Format: Article
Language:English
Published: Hindawi Limited 1998-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1998/324920
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spelling doaj-f0b02d7774014107a75658d0493537482021-07-02T07:40:22ZengHindawi LimitedCanadian Respiratory Journal1198-22411998-01-015210110810.1155/1998/324920Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in SmokersDJ Cotton0JT Mink1BL Graham2Division of Respiratory Medicine, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaDivision of Respiratory Medicine, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaDivision of Respiratory Medicine, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaBACKGROUND: Although centrilobular emphysema, and small airway, interstitial and alveoli inflammation can be detected pathologically in the lungs of smokers with relatively well preserved lung function, these changes are difficult to assess using available physiological tests. Because submaximal single breath washout (SBWSM) manoeuvres improve the detection of abnormalities in ventilation inhomogeneity in the lung periphery in smokers compared with traditional vital capacity manoeuvres, SBWSM manoeuvres were used in this study to measure temporal differences in diffusing capacity using a rapid response carbon monoxide analyzer.http://dx.doi.org/10.1155/1998/324920
collection DOAJ
language English
format Article
sources DOAJ
author DJ Cotton
JT Mink
BL Graham
spellingShingle DJ Cotton
JT Mink
BL Graham
Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers
Canadian Respiratory Journal
author_facet DJ Cotton
JT Mink
BL Graham
author_sort DJ Cotton
title Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers
title_short Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers
title_full Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers
title_fullStr Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers
title_full_unstemmed Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers
title_sort nonuniformity of diffusing capacity from small alveolar gas samples is increased in smokers
publisher Hindawi Limited
series Canadian Respiratory Journal
issn 1198-2241
publishDate 1998-01-01
description BACKGROUND: Although centrilobular emphysema, and small airway, interstitial and alveoli inflammation can be detected pathologically in the lungs of smokers with relatively well preserved lung function, these changes are difficult to assess using available physiological tests. Because submaximal single breath washout (SBWSM) manoeuvres improve the detection of abnormalities in ventilation inhomogeneity in the lung periphery in smokers compared with traditional vital capacity manoeuvres, SBWSM manoeuvres were used in this study to measure temporal differences in diffusing capacity using a rapid response carbon monoxide analyzer.
url http://dx.doi.org/10.1155/1998/324920
work_keys_str_mv AT djcotton nonuniformityofdiffusingcapacityfromsmallalveolargassamplesisincreasedinsmokers
AT jtmink nonuniformityofdiffusingcapacityfromsmallalveolargassamplesisincreasedinsmokers
AT blgraham nonuniformityofdiffusingcapacityfromsmallalveolargassamplesisincreasedinsmokers
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