Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8).

Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8).

We have identified the zinc-finger transcription factor Kruppel-like factor 4 (Klf4) among the transcription factors that are significantly downregulated in their expression during epithelial-mesenchymal transition (EMT) in mammary epithelial cells and in breast cancer cells. Loss and gain of functi...

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Bibliographic Details
Main Authors: Neha Tiwari, Nathalie Meyer-Schaller, Phil Arnold, Helena Antoniadis, Mikhail Pachkov, Erik van Nimwegen, Gerhard Christofori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3581489?pdf=render

Internet

http://europepmc.org/articles/PMC3581489?pdf=render

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