Glucose-sensitive acetylation of Seryl tRNA synthetase regulates lipid synthesis in breast cancer
Abstract Abnormally enhanced de novo lipid biosynthesis has been increasingly realized to play crucial roles in the initiation and progression of varieties of cancers including breast cancer. However, the mechanisms underlying the dysregulation of lipid biosynthesis in breast cancer remain largely u...
Main Authors: | Jin Zhao, Hangming Bai, Xiaoyu Li, Jie Yan, Gengyi Zou, Longlong Wang, Xiru Li, Ze Liu, Rong Xiang, Xiang-Lei Yang, Yi Shi |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Signal Transduction and Targeted Therapy |
Online Access: | https://doi.org/10.1038/s41392-021-00714-0 |
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