Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma

Serous psammocarcinoma is a rare variant of serous carcinoma arising from either ovary or peritoneum, characterized by massive psammoma body formation, low grade cytologic features, and invasiveness. Its clinical behavior is similar to serous borderline tumors with relatively favorable prognosis. We...

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Main Authors: Saubhagya Kumar Jena, Pritinanda Mishra, Vandana Mohapatra, Sweta Singh
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2015/531242
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spelling doaj-f0a93859882d4a89b92abbb14147332b2020-11-24T22:57:00ZengHindawi LimitedCase Reports in Obstetrics and Gynecology2090-66842090-66922015-01-01201510.1155/2015/531242531242Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous CarcinomaSaubhagya Kumar Jena0Pritinanda Mishra1Vandana Mohapatra2Sweta Singh3Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Bhubaneswar, Odisha 751019, IndiaDepartment of Pathology and Laboratory Medicine, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Bhubaneswar, Odisha 751019, IndiaDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Bhubaneswar, Odisha 751019, IndiaDepartment of Obstetrics & Gynaecology, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Bhubaneswar, Odisha 751019, IndiaSerous psammocarcinoma is a rare variant of serous carcinoma arising from either ovary or peritoneum, characterized by massive psammoma body formation, low grade cytologic features, and invasiveness. Its clinical behavior is similar to serous borderline tumors with relatively favorable prognosis. We report herein a case of a 60-year-old postmenopausal woman who presented with abdominal distension. Contrast enhanced computed tomography (CECT) revealed calcified pelvic masses with ascites. Elevated serum CA-125 (970 U/mL) suggested malignant ovarian neoplasm. Patient underwent exploratory laparotomy with primary debulking surgery. Histopathology showed bilateral serous psammocarcinoma of ovary with invasive implants on omentum. Adjuvant chemotherapy was advised in view of advanced stage disease, although its benefits are poorly defined due to rarity of the tumor. However, patient opted out of it and is now on follow-up.http://dx.doi.org/10.1155/2015/531242
collection DOAJ
language English
format Article
sources DOAJ
author Saubhagya Kumar Jena
Pritinanda Mishra
Vandana Mohapatra
Sweta Singh
spellingShingle Saubhagya Kumar Jena
Pritinanda Mishra
Vandana Mohapatra
Sweta Singh
Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
Case Reports in Obstetrics and Gynecology
author_facet Saubhagya Kumar Jena
Pritinanda Mishra
Vandana Mohapatra
Sweta Singh
author_sort Saubhagya Kumar Jena
title Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
title_short Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
title_full Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
title_fullStr Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
title_full_unstemmed Bilateral Serous Psammocarcinoma of Ovary: Rare Variant Low Grade Serous Carcinoma
title_sort bilateral serous psammocarcinoma of ovary: rare variant low grade serous carcinoma
publisher Hindawi Limited
series Case Reports in Obstetrics and Gynecology
issn 2090-6684
2090-6692
publishDate 2015-01-01
description Serous psammocarcinoma is a rare variant of serous carcinoma arising from either ovary or peritoneum, characterized by massive psammoma body formation, low grade cytologic features, and invasiveness. Its clinical behavior is similar to serous borderline tumors with relatively favorable prognosis. We report herein a case of a 60-year-old postmenopausal woman who presented with abdominal distension. Contrast enhanced computed tomography (CECT) revealed calcified pelvic masses with ascites. Elevated serum CA-125 (970 U/mL) suggested malignant ovarian neoplasm. Patient underwent exploratory laparotomy with primary debulking surgery. Histopathology showed bilateral serous psammocarcinoma of ovary with invasive implants on omentum. Adjuvant chemotherapy was advised in view of advanced stage disease, although its benefits are poorly defined due to rarity of the tumor. However, patient opted out of it and is now on follow-up.
url http://dx.doi.org/10.1155/2015/531242
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