Enhanced Therapeutic Potential of the Secretome Released from Adipose-Derived Stem Cells by PGC-1α-Driven Upregulation of Mitochondrial Proliferation

Enhanced Therapeutic Potential of the Secretome Released from Adipose-Derived Stem Cells by PGC-1α-Driven Upregulation of Mitochondrial Proliferation

Peroxisome proliferator activated receptor λ coactivator 1α (PGC-1α) is a potent regulator of mitochondrial biogenesis and energy metabolism. In this study, we investigated the therapeutic potential of the secretome released from the adipose-derived stem cells (ASCs) trans...

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Bibliographic Details
Main Authors: Jaeim Lee, Ok-Hee Kim, Sang Chul Lee, Kee-Hwan Kim, Jin Sun Shin, Ha-Eun Hong, Ho Joong Choi, Say-June Kim
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
adipose-derived stem cell
liver regeneration
reactive oxygen species
peroxisome proliferator activated receptor λ coactivator 1α (pgc-1α)
secretome
Online Access:https://www.mdpi.com/1422-0067/20/22/5589

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https://www.mdpi.com/1422-0067/20/22/5589

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