Liver X receptor agonist ameliorates amyloid β-induced inflammation and apoptosis in retinal pigment epithelial cells by activating SIRT1 signaling cascade
Objective To investigate the role of liver X receptor (LXR)-SIRT1 regulatory axis in inflammation and apoptosis of retinal pigment epithelial (RPE) cells induced by β-amyloid (Aβ). Methods Human peripheral blood mononuclear cells (PBMCs) were collected from patients with wet age-related macular dege...
Main Authors: | GAN Min, ZHOU Qiaoya, HONG Meijing, LI Xue, PENG Hui |
---|---|
Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Third Military Medical University
2020-07-01
|
Series: | Di-san junyi daxue xuebao |
Subjects: | |
Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/202003092.htm |
Similar Items
-
Differential changes in gene expression in cultured human retinal pigment epithelial cells after beta-amyloid stimulation
by: Kurji, Khaliq
Published: (2008) -
Differential changes in gene expression in cultured human retinal pigment epithelial cells after beta-amyloid stimulation
by: Kurji, Khaliq
Published: (2008) -
Differential changes in gene expression in cultured human retinal pigment epithelial cells after beta-amyloid stimulation
by: Kurji, Khaliq
Published: (2008) -
Amyloid beta deposition related retinal pigment epithelium cell impairment and subretinal microglia activation in aged APPswePS1 transgenic mice
by: Zhi-Zhang Dong, et al.
Published: (2018-05-01) -
Intravitreal gas injection with prone positioning for giant retinal pigment epithelial tear
by: Deependra Vikram Singh, et al.
Published: (2018-01-01)