Genetic Variations of Oxidative Stress Related Genes ALOX5, ALOX5AP and MPO Modulate Ischemic Stroke Susceptibility Through Main Effects and Epistatic Interactions in a Chinese Population

Genetic Variations of Oxidative Stress Related Genes ALOX5, ALOX5AP and MPO Modulate Ischemic Stroke Susceptibility Through Main Effects and Epistatic Interactions in a Chinese Population

Background/Aims: To investigate the roles of the oxidative stress related-genes ALOX5, ALOX5AP and MPO in ischemic stroke susceptibility in the Han Chinese population. Methods: A total of 351 ischemic stroke patients and 417 controls were recruited. The ALOX5 rs10900213, ALOX5AP rs4293222 and MPO rs...

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Bibliographic Details
Main Authors: Ding Liu, Lei Liu, Zhi Song, Zhongyang Hu, Jia Liu, Deren Hou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Oxidative stress
ALOX5 gene
ALOX5AP gene
MPO gene
Genetic main effects
Epistatic interactions
Ischemic stroke susceptibility
Ischemic stroke prognosis
Online Access:https://www.karger.com/Article/FullText/482023

Internet

https://www.karger.com/Article/FullText/482023

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