RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples

RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples

Abstract Background RNA sequencing (RNA-seq) and microarrays are two transcriptomics techniques aimed at the quantification of transcribed genes and their isoforms. Here we compare the latest Affymetrix HTA 2.0 microarray with Illumina 2000 RNA-seq for the analysis of patient samples - normal lung e...

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Bibliographic Details
Main Authors: Petr V. Nazarov, Arnaud Muller, Tony Kaoma, Nathalie Nicot, Cristina Maximo, Philippe Birembaut, Nhan L. Tran, Gunnar Dittmar, Laurent Vallar
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Genomics
Subjects:
Microarrays
RNA sequencing
Differential expression analysis
Differential exon usage
Splicing
Online Access:http://link.springer.com/article/10.1186/s12864-017-3819-y

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