Reduced Mismatch Negativity is Associated with Increased Plasma Level of Glutamate in First-episode Psychosis

Abstract Reduced amplitude of mismatch negativity (MMN) is one of the more promising biological markers of schizophrenia. This finding holds true in both early and chronic phases of the disorder, and is compatible with the glutamatergic dysfunction hypothesis. To further establish MMN as a biomarker...

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Bibliographic Details
Main Authors: Tatsuya Nagai, Kenji Kirihara, Mariko Tada, Daisuke Koshiyama, Shinsuke Koike, Motomu Suga, Tsuyoshi Araki, Kenji Hashimoto, Kiyoto Kasai
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02267-1