Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage

Writing data in DNA is still a bottleneck due to the reliance on chemical synthesis methods. Here the authors report multiplexed enzymatic DNA synthesis using maskless photolithography.

Bibliographic Details
Main Authors:	Howon Lee, Daniel J. Wiegand, Kettner Griswold, Sukanya Punthambaker, Honggu Chun, Richie E. Kohman, George M. Church
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-18681-5

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spelling	doaj-f0694cb516a3421f8daca6541c619c5f2021-05-11T08:35:38ZengNature Publishing GroupNature Communications2041-17232020-10-011111910.1038/s41467-020-18681-5Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storageHowon Lee0Daniel J. Wiegand1Kettner Griswold2Sukanya Punthambaker3Honggu Chun4Richie E. Kohman5George M. Church6Department of Genetics, Harvard Medical SchoolDepartment of Genetics, Harvard Medical SchoolDepartment of Genetics, Harvard Medical SchoolDepartment of Genetics, Harvard Medical SchoolDepartment of Biomedical Engineering, Korea UniversityDepartment of Genetics, Harvard Medical SchoolDepartment of Genetics, Harvard Medical SchoolWriting data in DNA is still a bottleneck due to the reliance on chemical synthesis methods. Here the authors report multiplexed enzymatic DNA synthesis using maskless photolithography.https://doi.org/10.1038/s41467-020-18681-5
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Howon Lee Daniel J. Wiegand Kettner Griswold Sukanya Punthambaker Honggu Chun Richie E. Kohman George M. Church
spellingShingle	Howon Lee Daniel J. Wiegand Kettner Griswold Sukanya Punthambaker Honggu Chun Richie E. Kohman George M. Church Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage Nature Communications
author_facet	Howon Lee Daniel J. Wiegand Kettner Griswold Sukanya Punthambaker Honggu Chun Richie E. Kohman George M. Church
author_sort	Howon Lee
title	Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage
title_short	Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage
title_full	Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage
title_fullStr	Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage
title_full_unstemmed	Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage
title_sort	photon-directed multiplexed enzymatic dna synthesis for molecular digital data storage
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-10-01
description	Writing data in DNA is still a bottleneck due to the reliance on chemical synthesis methods. Here the authors report multiplexed enzymatic DNA synthesis using maskless photolithography.
url	https://doi.org/10.1038/s41467-020-18681-5
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Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage

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