Single-dose local intraosseous injection of simvastatin suppresses breast cancer with tumor vascular normalization

Tumor vessels play important roles in cancer development and angiogenesis has been characterized as an essential process for tumor cell tumor growth. Our previous studies found that a single-dose local intraosseous simvastatin injection rapidly and long-termly mobilized bone marrow-derived endotheli...

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Bibliographic Details
Main Authors: Wanqiong Yuan, Bao Hai, Xiaoqing Ren, Junxiong Zhu, Chenggui Zhang, Zhiyuan Guan, Jialin Jia, Hong Wang, Baoshan Cao, Chunli Song
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320303594