Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells

Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells

<p>Abstract</p> <p>Background</p> <p>Resistance to chemotherapy remains one of the principle obstacles to the treatment of colon cancer. In order to identify the molecular mechanism of this resistance, we investigated the role of the steroid and xenobiotic receptor (SXR...

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Bibliographic Details
Main Authors:	Boisdron-Celle Michèle, de Carné Trécesson Sophie, Preisser Laurence, Basseville Agnes, Gamelin Erick, Coqueret Olivier, Morel Alain
Format:	Article
Language:	English
Published:	BMC 2011-07-01
Series:	Molecular Cancer
Online Access:	http://www.molecular-cancer.com/content/10/1/80

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