RORα Suppresses Epithelial-to-Mesenchymal Transition and Invasion in Human Gastric Cancer Cells via the Wnt/β-Catenin Pathway

RORα Suppresses Epithelial-to-Mesenchymal Transition and Invasion in Human Gastric Cancer Cells via the Wnt/β-Catenin Pathway

Retinoid-related orphan receptor alpha (RORα) is involved in tumor development. However, the mechanisms underlying RORα inhibiting epithelial-to-mesenchymal transition (EMT) and invasion are poorly understood in gastric cancer (GC). This study revealed that the decreased expression of RORα is associ...

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Bibliographic Details
Main Authors: Jian Su, Bo Su, Hong Xia, Fang Liu, XiaoHong Zhao, Juan Li, JiZhen Zhang, Ying Shi, Ying Zeng, Xi Zeng, Hui Ling, YouHua Wu, Qi Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
RORα
Wnt/β-catenin pathway
proliferation
epithelial-to-mesenchymal transition
invasion
human gastric cancer
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01344/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01344/full

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