The role of BRCA1/2 in hereditary and familial breast and ovarian cancers

The role of BRCA1/2 in hereditary and familial breast and ovarian cancers

Abstract Background BRCA1/2 pathogenic variants have become associated with familial breast and ovarian cancers, and hereditary cancer‐predisposition syndrome. With advances in molecular biology, BRCA profiling facilitates early diagnosis and the implementation of preventive and therapeutic strategi...

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Bibliographic Details
Main Authors: Yousef M. Hawsawi, Nouf S. Al‐Numair, Turki M. Sobahy, Areej M. Al‐Ajmi, Raneem M. Al‐Harbi, Mohammed A. Baghdadi, Atif A. Oyouni, Osama M. Alamer
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
BRCA1
BRCA2
breast cancer
founder effect
genetics
variant
Online Access:https://doi.org/10.1002/mgg3.879

Internet

https://doi.org/10.1002/mgg3.879

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