Yield and Clinical Predictors of Thoracic Spine Injury from Chest Computed Tomography for Blunt Trauma

Introduction: Cost and radiation risk have prompted intense examination of trauma patient imaging. A proposed decision instrument (DI) for the use of chest computed tomography (CT), (CCT) in blunt trauma patients includes thoracic spine (TS) tenderness, altered mental status (AMS) and distracting pa...

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Main Authors: Mark I. Langdorf, Nadia Zuabi, Nooreen A. Khan, Chelsey Bithell, Armaan A. Rowther, Karin Reed, Craig L. Anderson, Shahram Lotfipour, Robert Rodriguez
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2014-07-01
Series:Western Journal of Emergency Medicine
Online Access:http://escholarship.org/uc/item/08q5w191
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spelling doaj-f03867a6dd134afeb7f5beafdbfb009f2020-11-24T22:43:27ZengeScholarship Publishing, University of CaliforniaWestern Journal of Emergency Medicine1936-900X1936-900X2014-07-0115446547010.5811/westjem.2014.4.20672Yield and Clinical Predictors of Thoracic Spine Injury from Chest Computed Tomography for Blunt TraumaMark I. Langdorf,0Nadia Zuabi1Nooreen A. Khan,2Chelsey Bithell3Armaan A. Rowther4Karin Reed5Craig L. Anderson,6Shahram Lotfipour7Robert Rodriguez8University of California Irvine, Department of Emergency Medicine, Irvine, CaliforniaUniversity of California Irvine, Department of Emergency Medicine, Irvine, CaliforniaUniversity of California Irvine, Department of Emergency Medicine, Irvine, CaliforniaUniversity of California Irvine, Department of Emergency Medicine, Irvine, CaliforniaUniversity of California Irvine, Department of Emergency Medicine, Irvine, CaliforniaUniversity of California Irvine, Department of Emergency Medicine, Irvine, CaliforniaUniversity of California Irvine, Department of Emergency Medicine, Irvine, CaliforniaUniversity of California Irvine, Department of Emergency Medicine, Irvine, CaliforniaUniversity of California San Francisco, Department of Emergency Medicine, San Francisco, CaliforniaIntroduction: Cost and radiation risk have prompted intense examination of trauma patient imaging. A proposed decision instrument (DI) for the use of chest computed tomography (CT), (CCT) in blunt trauma patients includes thoracic spine (TS) tenderness, altered mental status (AMS) and distracting painful injury (DPI) as potential predictor variables. TS CT is a separate, costly study whose value is currently ill-defined. The objective of this study is to determine test characteristics of these predictor variables alone, and in combination, to derive a TS injury DI. Methods: Prospective cohort study of blunt trauma patients age > 14 in a Level I Trauma Center who had either CCT or TS CT. Results: Of 1,798 blunt trauma patients, 1,174 (65.3%) had CCT, and 46 (2.6%) had a TS CT at physician discretion. CCT identified 58 TS injuries in 1,220 patients (4.8%). For 1,032 patients without AMS, 18/35 had TS tenderness, for sensitivity of 51.4%, specificity 84.7%, positive (PPV) and negative predictive values (NPV) of 10.5% and 98.0%. Positive likelihood ratio (+LR) was 3.35, with negative (-LR) 0.57. Among the 58 TS injuries, 23 had AMS for sensitivity of 39.7%, with other test characteristics of 85.8%, 12.2%, 96.6%, with +LR 2.79 and -LR 0.70. Thirty-eight of 58 had DPI, for sensitivity 65.5%, with other test characteristics 65.7%, 8.7%, and 97.4%, with +LR 1.91 and -LR 0.52. Combining 3 predictor variables into a proposed DI found 56/58 injuries for test characteristics of 96.6% (95% CI 88.1-99.6%), 49.1% (46.1-52.0%), 8.6% (6.6-11.1%) and 99.7% (CI 98.7-100%), with +LR 1.90 (1.76-2.04) and -LR 0.07 (0.02-0.28). If validated, the DI would exclude 572/1,220 CCT patients from separate TS CT (46.9%, CI 44.1-49.7%), and 141/511 (27.6%, CI 23.8-31.7%) patients who actually had TS CT in our cohort. Medicare payment at our center for sagittal reconstructions of TS CT is $280 for professional plus technical charges ($3,312 per study). The DI, if validated, would save $39,000 –$160,000 in TS imaging payments. Conclusion: TS CT is low yield and costly. Patients who are alert, have no TS tenderness and no DPI have a very low likelihood of TS injury (NPV 99.7% 95% CI lower limit 98.7%) with –LR=0.07, 95% CI upper limit 0.28). Avoiding TS CT may save considerable charges and payments.[West J Emerg Med. 2014;15(4):465–470.]http://escholarship.org/uc/item/08q5w191
collection DOAJ
language English
format Article
sources DOAJ
author Mark I. Langdorf,
Nadia Zuabi
Nooreen A. Khan,
Chelsey Bithell
Armaan A. Rowther
Karin Reed
Craig L. Anderson,
Shahram Lotfipour
Robert Rodriguez
spellingShingle Mark I. Langdorf,
Nadia Zuabi
Nooreen A. Khan,
Chelsey Bithell
Armaan A. Rowther
Karin Reed
Craig L. Anderson,
Shahram Lotfipour
Robert Rodriguez
Yield and Clinical Predictors of Thoracic Spine Injury from Chest Computed Tomography for Blunt Trauma
Western Journal of Emergency Medicine
author_facet Mark I. Langdorf,
Nadia Zuabi
Nooreen A. Khan,
Chelsey Bithell
Armaan A. Rowther
Karin Reed
Craig L. Anderson,
Shahram Lotfipour
Robert Rodriguez
author_sort Mark I. Langdorf,
title Yield and Clinical Predictors of Thoracic Spine Injury from Chest Computed Tomography for Blunt Trauma
title_short Yield and Clinical Predictors of Thoracic Spine Injury from Chest Computed Tomography for Blunt Trauma
title_full Yield and Clinical Predictors of Thoracic Spine Injury from Chest Computed Tomography for Blunt Trauma
title_fullStr Yield and Clinical Predictors of Thoracic Spine Injury from Chest Computed Tomography for Blunt Trauma
title_full_unstemmed Yield and Clinical Predictors of Thoracic Spine Injury from Chest Computed Tomography for Blunt Trauma
title_sort yield and clinical predictors of thoracic spine injury from chest computed tomography for blunt trauma
publisher eScholarship Publishing, University of California
series Western Journal of Emergency Medicine
issn 1936-900X
1936-900X
publishDate 2014-07-01
description Introduction: Cost and radiation risk have prompted intense examination of trauma patient imaging. A proposed decision instrument (DI) for the use of chest computed tomography (CT), (CCT) in blunt trauma patients includes thoracic spine (TS) tenderness, altered mental status (AMS) and distracting painful injury (DPI) as potential predictor variables. TS CT is a separate, costly study whose value is currently ill-defined. The objective of this study is to determine test characteristics of these predictor variables alone, and in combination, to derive a TS injury DI. Methods: Prospective cohort study of blunt trauma patients age > 14 in a Level I Trauma Center who had either CCT or TS CT. Results: Of 1,798 blunt trauma patients, 1,174 (65.3%) had CCT, and 46 (2.6%) had a TS CT at physician discretion. CCT identified 58 TS injuries in 1,220 patients (4.8%). For 1,032 patients without AMS, 18/35 had TS tenderness, for sensitivity of 51.4%, specificity 84.7%, positive (PPV) and negative predictive values (NPV) of 10.5% and 98.0%. Positive likelihood ratio (+LR) was 3.35, with negative (-LR) 0.57. Among the 58 TS injuries, 23 had AMS for sensitivity of 39.7%, with other test characteristics of 85.8%, 12.2%, 96.6%, with +LR 2.79 and -LR 0.70. Thirty-eight of 58 had DPI, for sensitivity 65.5%, with other test characteristics 65.7%, 8.7%, and 97.4%, with +LR 1.91 and -LR 0.52. Combining 3 predictor variables into a proposed DI found 56/58 injuries for test characteristics of 96.6% (95% CI 88.1-99.6%), 49.1% (46.1-52.0%), 8.6% (6.6-11.1%) and 99.7% (CI 98.7-100%), with +LR 1.90 (1.76-2.04) and -LR 0.07 (0.02-0.28). If validated, the DI would exclude 572/1,220 CCT patients from separate TS CT (46.9%, CI 44.1-49.7%), and 141/511 (27.6%, CI 23.8-31.7%) patients who actually had TS CT in our cohort. Medicare payment at our center for sagittal reconstructions of TS CT is $280 for professional plus technical charges ($3,312 per study). The DI, if validated, would save $39,000 –$160,000 in TS imaging payments. Conclusion: TS CT is low yield and costly. Patients who are alert, have no TS tenderness and no DPI have a very low likelihood of TS injury (NPV 99.7% 95% CI lower limit 98.7%) with –LR=0.07, 95% CI upper limit 0.28). Avoiding TS CT may save considerable charges and payments.[West J Emerg Med. 2014;15(4):465–470.]
url http://escholarship.org/uc/item/08q5w191
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