Targeting Insulin-Like Growth Factor Binding Protein-3 Signaling in Triple-Negative Breast Cancer

Targeting Insulin-Like Growth Factor Binding Protein-3 Signaling in Triple-Negative Breast Cancer

Insulin-like growth factor binding protein-3 (IGFBP-3) is a key regulatory molecule of the IGF axis and can function in a tissue-specific way as both a tumor suppressor and promoter. Triple-negative breast cancer (TNBC) has high tumor expression of IGFBP-3 associated with markers of poor prognosis a...

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Bibliographic Details
Main Authors:	Kamila A. Marzec, Robert C. Baxter, Janet L. Martin
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2015/638526

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