Alendronate (ALN) combined with Osteoprotegerin (OPG) significantly improves mechanical properties of long bone than the single use of ALN or OPG in the ovariectomized rats

Alendronate (ALN) combined with Osteoprotegerin (OPG) significantly improves mechanical properties of long bone than the single use of ALN or OPG in the ovariectomized rats

<p>Abstract</p> <p>Background</p> <p>Alendronate (ALN) is the most common form of bisphosphonates used for the treatment of osteoporosis. Osteoprotegerin (OPG) has also been shown to reduce osteoporotic changes in both humans and experimental animals after systemic admi...

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Bibliographic Details
Main Authors: Chan Kai-Ming, Tang Pei-Fu, Huang Peng, Wang Yan, Li Gang
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoprotegerin
Alendronate
RANKL
Osteoporosis
Ovariectomy
Online Access:http://www.josr-online.com/content/6/1/34

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