Nicotinic Receptor Activity Alters Synaptic Plasticity

Nicotinic Receptor Activity Alters Synaptic Plasticity

Studies using specific agonists, antagonists, and lesions have shown that nicotinic cholinergic systems participate in attention, learning, and memory[1,2]. The nicotinic manipulations usually have the greatest influence on difficult tasks or on cognitively impaired subjects[2]. For example, Alzheim...

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Main Author: John A. Dani
Format: Article
Language:English
Published: Hindawi Limited 2001-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2001.74
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spelling doaj-f022aeae6d77405c8cf5acaec93452152020-11-24T20:56:09ZengHindawi LimitedThe Scientific World Journal1537-744X2001-01-01139339510.1100/tsw.2001.74Nicotinic Receptor Activity Alters Synaptic PlasticityJohn A. Dani0Division of Neurology, Baylor College of Medicine, Houston, TX 77030-3498, USAStudies using specific agonists, antagonists, and lesions have shown that nicotinic cholinergic systems participate in attention, learning, and memory[1,2]. The nicotinic manipulations usually have the greatest influence on difficult tasks or on cognitively impaired subjects[2]. For example, Alzheimer's disease is characterized by a loss of cholinergic projections and nicotinic acetylcholine receptors (nAChRs) in the cortex and hippocampus[3]. Nicotine skin patches can improve learning rates and attention in Alzheimer's patients[4].http://dx.doi.org/10.1100/tsw.2001.74
collection DOAJ
language English
format Article
sources DOAJ
author John A. Dani
spellingShingle John A. Dani
Nicotinic Receptor Activity Alters Synaptic Plasticity
The Scientific World Journal
author_facet John A. Dani
author_sort John A. Dani
title Nicotinic Receptor Activity Alters Synaptic Plasticity
title_short Nicotinic Receptor Activity Alters Synaptic Plasticity
title_full Nicotinic Receptor Activity Alters Synaptic Plasticity
title_fullStr Nicotinic Receptor Activity Alters Synaptic Plasticity
title_full_unstemmed Nicotinic Receptor Activity Alters Synaptic Plasticity
title_sort nicotinic receptor activity alters synaptic plasticity
publisher Hindawi Limited
series The Scientific World Journal
issn 1537-744X
publishDate 2001-01-01
description Studies using specific agonists, antagonists, and lesions have shown that nicotinic cholinergic systems participate in attention, learning, and memory[1,2]. The nicotinic manipulations usually have the greatest influence on difficult tasks or on cognitively impaired subjects[2]. For example, Alzheimer's disease is characterized by a loss of cholinergic projections and nicotinic acetylcholine receptors (nAChRs) in the cortex and hippocampus[3]. Nicotine skin patches can improve learning rates and attention in Alzheimer's patients[4].
url http://dx.doi.org/10.1100/tsw.2001.74
work_keys_str_mv AT johnadani nicotinicreceptoractivityalterssynapticplasticity
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