USP2-Related Cellular Signaling and Consequent Pathophysiological Outcomes

USP2-Related Cellular Signaling and Consequent Pathophysiological Outcomes

Ubiquitin specific protease (USP) 2 is a multifunctional deubiquitinating enzyme. USP2 modulates cell cycle progression, and therefore carcinogenesis, via the deubiquitination of cyclins and Aurora-A. Other tumorigenic molecules, including epidermal growth factor and fatty acid synthase, are also ta...

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Bibliographic Details
Main Authors: Hiroshi Kitamura, Mayuko Hashimoto
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
ubiquitin-specific protease
tumorigenesis
cell cycle
inflammation
circadian clock
metabolic disorder
Online Access:https://www.mdpi.com/1422-0067/22/3/1209

Internet

https://www.mdpi.com/1422-0067/22/3/1209

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