uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma.

BACKGROUND:Meningiomas are the most commonly occurring intracranial tumors and account for approximately 15-20% of central nervous system tumors. Surgery and radiation therapy is a common treatment for brain tumors, however, patients whose tumors recur after such treatments have limited therapeutic...

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Main Authors: Reshu Gupta, Arun Kumar Nalla, Venkateswara Rao Gogineni, Chandramu Chetty, Praveen Bhoopathi, Jeffrey D Klopfenstein, Andrew J Tsung, Sanjeeva Mohanam, Jasti S Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21347260/pdf/?tool=EBI

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