uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma.
BACKGROUND:Meningiomas are the most commonly occurring intracranial tumors and account for approximately 15-20% of central nervous system tumors. Surgery and radiation therapy is a common treatment for brain tumors, however, patients whose tumors recur after such treatments have limited therapeutic...
Main Authors: | Reshu Gupta, Arun Kumar Nalla, Venkateswara Rao Gogineni, Chandramu Chetty, Praveen Bhoopathi, Jeffrey D Klopfenstein, Andrew J Tsung, Sanjeeva Mohanam, Jasti S Rao |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-02-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21347260/pdf/?tool=EBI |
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