The CRISPR associated protein Cas4 Is a 5' to 3' DNA exonuclease with an iron-sulfur cluster.
The Cas4 protein is one of the core CRISPR-associated (Cas) proteins implicated in the prokaryotic CRISPR system for antiviral defence. Cas4 is thought to play a role in the capture of new viral DNA sequences for incorporation into the host genome. No biochemical activity has been reported for Cas4,...
Main Authors: | Jing Zhang, Taciana Kasciukovic, Malcolm F White |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3466216?pdf=render |
Similar Items
-
Biochemical studies on T5 exonuclease
by: Zhang, Jing
Published: (2012) -
Reactions of iron-sulfur clusters in proteins
by: Fawcett, Sarah E. J.
Published: (1998) -
Structure-specific DNA cleavage and binding by bacteriophage T5 5'-3' exonuclease
by: Garforth, Scott John
Published: (1998) -
Biogenesis of Iron–Sulfur Clusters and Their Role in DNA Metabolism
by: Ruifeng Shi, et al.
Published: (2021-09-01) -
Defining the role of cytosolic iron-sulfur cluster assembly targeting complex in identification of iron-sulfur cluster proteins
by: Vo, Amanda T.
Published: (2019)