Changes in Glucose and Glutamine Lymphocyte Metabolisms Induced by Type I Interferon α

In lymphocytes (LY), the well-documented antiproliferative effects of IFN-α are associated with inhibition of protein synthesis, decreased amino acid incorporation, and cell cycle arrest. However, the effects of this cytokine on the metabolism of glucose and glutamine in these cells have not been we...

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Main Authors: Francisco Navarro, Aline V. N. Bacurau, Andréa Vanzelli, Marcela Meneguello-Coutinho, Marco C. Uchida, Milton R. Moraes, Sandro S. Almeida, Frederick Wasinski, Carlos C. Barros, Martin Würtele, Ronaldo C. Araújo, Luís F. B. Costa Rosa, Reury F. P. Bacurau
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2010/364290