Autologous Fibrin Sealant in Tubeless Percutaneous Nephrolithotomy; A Prospective Study

• Main Authors: Seyyed Amir Mohsen Ziaee, Reza Sarhangnejad, Hassan Abolghasemi, Peyman Eshghi, Mohammad Hadi Radfar, Ali Ahanian, Muhammet Ihsan Karaman, Nasser Amirizadeh, Akbar Nouralizadeh
• Format: Article
• Language: English
• Published: Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences 2013-09-01
• Series: Urology Journal
• Subjects: Autologous Fibrin; Percutaneous Nephrolithotomy
• Online Access: http://www.urologyjournal.org/index.php/uj/article/view/1685/755

Purpose: To evaluate the efficacy of autologous single-donor fibrin glue after tubeless percutaneousnephrolithotomy (PCNL).Materials and Methods: Forty-three patients were planned for tubeless PCNL in a prospectivecohort study and randomized in two groups with or without using fibrin glue. Randomizationmethod was based on the computer-generated random numbers.Results: Transfusion, urinary leakage, or major complications were found in neither of thegroups. There was no difference between two groups in stone free rate (P = .53), and changesin hemoglobin (P = .61) and serum creatinine (P = .63) level.Conclusion: Although autologous fibrin glue did not play any significant role in improvingresults or decreasing complications after tubeless PCNL in our study, its use was safe and didnot increase complications.Keywords: percutaneous; surgery; kidney calculi, treatment outcome; fibrin tissue adhesive;wound closure techniques