Ethyl 4-(2-fluorophenyl)-6-methyl-2-thioxo-1-(<i>p</i>-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

The Biginelli reaction is a highly versatile reaction that leads to dihydropyrimidinones/thiones. This scaffold is reported as being a privileged structure due to its ability to interact with biological targets. Synthesis of ethyl 4-(2-fluorophenyl)-6-methyl-2-thioxo-1-(<i>p</i>-tolyl)-1...

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Bibliographic Details
Main Authors: Itamar Luís Gonçalves, Luciano Porto Kagami, Gustavo Machado das Neves, Liliana Rockenbach, Leonardo Davi, Alceu Felipe Soares, Solange Cristina Garcia, Vera Lucia Eifler-Lima
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2018/4/M1029