Comparison of atlas-based auto-segmentation accuracy for radiotherapy in prostate cancer

• Main Authors: Takahiro Aoyama, Hidetoshi Shimizu, Tomoki Kitagawa, Kazushi Yokoi, Yutaro Koide, Hiroyuki Tachibana, Kojiro Suzuki, Takeshi Kodaira
• Format: Article
• Language: English
• Published: Elsevier 2021-07-01
• Series: Physics and Imaging in Radiation Oncology
• Subjects: Atlas-based auto-segmentation; Contouring; Interobserver variation; Prostate cancer; Radiation oncology
• Online Access: http://www.sciencedirect.com/science/article/pii/S2405631621000476

Atlas-based auto-segmentation (ABS) procedure used in radiotherapy can be classified into two groups, one using one atlas per patient (sSM) and the other using multiple atlases (sMM). This study evaluated auto-contouring accuracy and contouring time in patients with prostate cancer using the two procedures. The Dice similarity coefficient of sMM was significantly better than that of sSM (prostate [median, 0.81 (range, 0.66–0.91) vs. 0.64 (0.27–0.71), p < 0.01], seminal vesicles [0.49 (0.31–0.80) vs. 0.18 (0.01–0.60), p < 0.05], and rectum [0.81 (0.37–0.91) vs. 0.57 (0.31–0.77), p < 0.01]). The median contouring times were 2.6 (sMM) and 1.3 min (sSM).