Disruption of tumor suppressor gene Hint1 leads to remodeling of the lipid metabolic phenotype of mouse liver[S]
A lipidomic and metabolomic investigation of serum and liver from mice was performed to gain insight into the tumor suppressor gene Hint1. A major reprogramming of lipid homeostasis was found in both serum and liver of Hint1-null (Hint−/−) mice, with significant changes in the levels of many lipid m...
Main Authors: | Diren Beyoğlu, Kristopher W. Krausz, Juliette Martin, Olivier Maurhofer, Juliane Dorow, Uta Ceglarek, Frank J. Gonzalez, Jean-François Dufour, Jeffrey R. Idle |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2014-11-01
|
Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752034983X |
Similar Items
-
Metabolomic and Lipidomic Biomarkers for Premalignant Liver Disease Diagnosis and Therapy
by: Diren Beyoğlu, et al.
Published: (2020-01-01) -
Metabolic Rewiring and the Characterization of Oncometabolites
by: Diren Beyoğlu, et al.
Published: (2021-06-01) -
Rapid characterization of the fatty acyl composition of complex lipids by collision-induced dissociation time-of-flight mass spectrometry
by: Steven Wynn Esch, et al.
Published: (2007-01-01) -
The gut microbiota modulates host energy and lipid metabolism in mice[S]
by: Vidya R. Velagapudi, et al.
Published: (2010-05-01) -
Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids
by: Caroline H. Johnson, et al.
Published: (2017-10-01)