Mutational analysis of dishevelled genes in zebrafish reveals distinct functions in embryonic patterning and gastrulation cell movements.

Wnt signaling plays critical roles in dorsoventral fate specification and anteroposterior patterning, as well as in morphogenetic cell movements. Dishevelled proteins, or Dvls, mediate the activation of Wnt/ß-catenin and Wnt/planar cell polarity pathways. There are at least three highly conserved Dv...

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Bibliographic Details
Main Authors: Yan-Yi Xing, Xiao-Ning Cheng, Yu-Long Li, Chong Zhang, Audrey Saquet, Yuan-Yuan Liu, Ming Shao, De-Li Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6095615?pdf=render