Miller Fisher Variant of Guillain-Barré Syndrome: A Case Report & Clinical Review

• Main Authors: Partha Pratim Das, Sarmistha Biswash, Md. Enamul Karim, Nigar Sultana Ahmed, Badrul Islam, Shekhar Kumar Mandal, Abu Hena Md. Raihanuzzaman Sarkar
• Format: Article
• Language: English
• Published: Bangabandhu Sheikh Mujib Medical University 2012-06-01
• Series: Bangabandhu Sheikh Mujib Medical University Journal
• Subjects: Abnormal reflex; areflexia; ataxia; Guillain-Barré syndrome; ophthalmoplegia; Nerve Conduction Velocity (NCV)
• Online Access: https://www.banglajol.info/index.php/BSMMUJ/article/view/11028
• ISSN: 2074-2908; 2224-7750

Miller Fisher syndrome (MFS) is an uncommon variant of Guillain-Barré syndrome (GBS). It is characterized by external ophthalmoplegia, ataxia, and areflexia. The incidence of MFS as a proportion of GBS was reported to be 1 to 5 % in western countries and considerably higher in Eastern Asia i.e. 19% in Taiwan and 25% in Japan. Here we report the clinical features of a patient who initially presented with ataxia then subsequently developed limb weakness, areflexia and ophthalmoplegia. CSF study and NCV study supported our clinical diagnosis. Patient was managed conservatively. No intravenous immunoglobulin was given but the patient gradually improved in symptoms including power, ataxia, ophthalmoparesis. After one month the patient was discharged from hospital with complete recovery. DOI: http://dx.doi.org/10.3329/bsmmuj.v5i1.11028 BSMMU J 2012; 5(1):69-71