A new specific succinate-glutamate metabolomic hallmark in SDHx-related paragangliomas.

A new specific succinate-glutamate metabolomic hallmark in SDHx-related paragangliomas.

Paragangliomas (PGLs) are frequently associated with germline mutations in genes involved in energy metabolism. The purpose of the present study was to assess whether the tumor metabolomic profile of patients with hereditary and apparently sporadic PGLs enables the distinction of different subtypes...

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Bibliographic Details
Main Authors: Alessio Imperiale, François-Marie Moussallieh, Frédéric Sebag, Laurent Brunaud, Anne Barlier, Karim Elbayed, Philippe Bachellier, Bernard Goichot, Karel Pacak, Izzie-Jacques Namer, David Taïeb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842321?pdf=render

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