Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload

Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload

Abstract Aims Sacubitril/valsartan (sac/val) has shown superior effect compared with blockade of the renin–angiotensin–aldosterone system in heart failure with reduced ejection fraction. We aimed to investigate effects of sac/val compared with valsartan in a pressure overload model of heart failure...

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Bibliographic Details
Main Authors: Einar Sjaastad Nordén, Bård Andre Bendiksen, Henriette Andresen, Kaja Knudsen Bergo, Emil Knut Espe, Almira Hasic, Ida Marie Hauge‐Iversen, Ioanni Veras, Rizwan I. Hussain, Ivar Sjaastad, Geir Christensen, Alessandro Cataliotti
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:ESC Heart Failure
Subjects:
Cardiac pressure overload
Sacubitril/valsartan
Heart failure
Therapy
Hypertrophy
Diastolic dysfunction
Online Access:https://doi.org/10.1002/ehf2.13177

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