A quantitative study of the influence of coprocessing of binders on the mechanical properties of paracetamol tablets

A quantitative study of the influence of coprocessing of binders on the mechanical properties of paracetamol tablets

A 2³ factorial experimental design has been used to quantitatively study individual and interaction effects of the nature of binder (N), concentration of binder (C) and the applied pressure (P) on two mechanical properties, namely, tensile strength (TS) and brittle fracture index (BFI), of paracetam...

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Bibliographic Details
Main Authors: Abayomi Tolulope Ogunjimi, Gbenga Alebiowu
Format: Article
Language:English
Published: Universidade de São Paulo 2010-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Coprocessamento
Goma Neem
Celulose microcristalina
Ligante
Resistência à ruptura
Índice de fragilidade
Paracetamol
Coprocessing
Neem gum
Microcrystalline cellulose
Binder
Tensile strength
Brittle fracture index
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200006

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200006

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