Rational Development of A Polycistronic Plasmid with A CpG-Free Bacterial Backbone as A Potential Tool for Direct Reprogramming

Rational Development of A Polycistronic Plasmid with A CpG-Free Bacterial Backbone as A Potential Tool for Direct Reprogramming

Objective: Induced pluripotent stem cells are generated from somatic cells by direct reprogramming. These reprogrammed pluripotent cells have different applications in biomedical fields such as regenerative medicine. Although viral vectors are widely used for efficient reprogramming, they have li...

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Bibliographic Details
Main Authors: Kianoush Dormiani, Hamid Mir Mohammad Sadeghi, Hojjat Sadeghi-Aliabadi, Mahboobeh Forouzanfar, Hossein Baharvand, Kamran Ghaedi, Mohammad Hossein Nasr-Esfahani
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2016-10-01
Series:Cell Journal
Subjects:
2A Peptide
CpG Dinucleotide
Extrachromosomal Plasmid
Polycistronic
Reprogramming
Online Access:http://celljournal.org/journal/article/6882/download

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