Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.

Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.

Selenium (Se) is an essential micronutrient that exerts its functions via selenoproteins. Little is known about the role of Se in inflammatory bowel disease (IBD). Epidemiological studies have inversely correlated nutritional Se status with IBD severity and colon cancer risk. Moreover, molecular stu...

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Main Authors: Caitlyn W Barrett, Kshipra Singh, Amy K Motley, Mary K Lintel, Elena Matafonova, Amber M Bradley, Wei Ning, Shenika V Poindexter, Bobak Parang, Vishruth K Reddy, Rupesh Chaturvedi, Barbara M Fingleton, Mary K Washington, Keith T Wilson, Sean S Davies, Kristina E Hill, Raymond F Burk, Christopher S Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701622?pdf=render

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