Proteoliposomes as matrix vesicles' biomimetics to study the initiation of skeletal mineralization

Proteoliposomes as matrix vesicles' biomimetics to study the initiation of skeletal mineralization

During the process of endochondral bone formation, chondrocytes and osteoblasts mineralize their extracellular matrix by promoting the formation of hydroxyapatite (HA) seed crystals in the sheltered interior of membrane-limited matrix vesicles (MVs). Ion transporters control the availability of phos...

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Bibliographic Details
Main Authors: A.M.S. Simão, M.C. Yadav, P. Ciancaglini, J.L. Millán
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2010-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Alkaline phosphatase
Biomineralization
Calcification
Lipids
Pyrophosphate
ATP
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300003

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