Fahr’s Syndrome

• Main Authors: Payam Saadat, Tahereh Hejazian, Reza Mohseni Ahangar
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2019-01-01
• Series: Case Reports in Clinical Practice
• Subjects: Fahr’s syndrome; Basal ganglia calcification; Brain; Magnetic Resonance Imaging (MRI)
• Online Access: https://crcp.tums.ac.ir/index.php/crcp/article/view/195

Fahr’s syndrome is a rare neurodegenerative disorder. Bilateral basal ganglia and dentate nuclei of the cerebellum are involved in this disorder and deposition of calcium is the hallmark of this syndrome. It has been recognized as a sporadic or inherited disease with variable presentations. In this article, we report a 40-year-old man with incidentally discovered brain calcifcation as the sole manifesation of Fahr’s syndrome. A 40-year-old male without any comorbidities was presented with brain calcifcation that was found incidentally. Brain imaging revealed symmetric calcifcations in bilateral basal ganglia, internal capsules, and cerebral white matter. This pattern of calcifcation is highly suspicious of Fahr’s syndrome. Other pathologic processes that could lead to intracranial calcifcation were excluded. We present a young patient with sporadic and asymptomatic Fahr’s syndrome after ruling out abnormalities of known calcium metabolism and developmental defects.