Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system

Urinary cells can be an ideal source for generating hiPSCs and progenitors, as they are easily accessible, non-invasive, and universally available. We generated human induced pluripotent stem cells (hiPSCs) from the urinary cells of a healthy donor using a Sendai virus-based gene delivery method. Th...

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Main Authors: Kyung-Ok Uhm, Eun Hee Jo, Gue Youn Go, So-Jung Kim, Hye Young Choi, Young Sam Im, Hye-Yeong Ha, Ji-Won Jung, Soo Kyung Koo
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117300636
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spelling doaj-ef479a14048f478db1641995b560e27a2020-11-24T21:26:46ZengElsevierStem Cell Research1873-50611876-77532017-05-0121C444610.1016/j.scr.2017.03.019Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration systemKyung-Ok UhmEun Hee JoGue Youn GoSo-Jung KimHye Young ChoiYoung Sam ImHye-Yeong HaJi-Won JungSoo Kyung KooUrinary cells can be an ideal source for generating hiPSCs and progenitors, as they are easily accessible, non-invasive, and universally available. We generated human induced pluripotent stem cells (hiPSCs) from the urinary cells of a healthy donor using a Sendai virus-based gene delivery method. The generated hiPSC line, KSCBi001-A, has a normal karyotype (46,XY). The pluripotency and capacity of multilineage differentiation were characterized by comparison with those of a human embryonic stem cell line. This cell line is registered and available from National Stem Cell Bank, Korea National Institute of Health.http://www.sciencedirect.com/science/article/pii/S1873506117300636
collection DOAJ
language English
format Article
sources DOAJ
author Kyung-Ok Uhm
Eun Hee Jo
Gue Youn Go
So-Jung Kim
Hye Young Choi
Young Sam Im
Hye-Yeong Ha
Ji-Won Jung
Soo Kyung Koo
spellingShingle Kyung-Ok Uhm
Eun Hee Jo
Gue Youn Go
So-Jung Kim
Hye Young Choi
Young Sam Im
Hye-Yeong Ha
Ji-Won Jung
Soo Kyung Koo
Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system
Stem Cell Research
author_facet Kyung-Ok Uhm
Eun Hee Jo
Gue Youn Go
So-Jung Kim
Hye Young Choi
Young Sam Im
Hye-Yeong Ha
Ji-Won Jung
Soo Kyung Koo
author_sort Kyung-Ok Uhm
title Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system
title_short Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system
title_full Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system
title_fullStr Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system
title_full_unstemmed Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system
title_sort generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system
publisher Elsevier
series Stem Cell Research
issn 1873-5061
1876-7753
publishDate 2017-05-01
description Urinary cells can be an ideal source for generating hiPSCs and progenitors, as they are easily accessible, non-invasive, and universally available. We generated human induced pluripotent stem cells (hiPSCs) from the urinary cells of a healthy donor using a Sendai virus-based gene delivery method. The generated hiPSC line, KSCBi001-A, has a normal karyotype (46,XY). The pluripotency and capacity of multilineage differentiation were characterized by comparison with those of a human embryonic stem cell line. This cell line is registered and available from National Stem Cell Bank, Korea National Institute of Health.
url http://www.sciencedirect.com/science/article/pii/S1873506117300636
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