Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system

Urinary cells can be an ideal source for generating hiPSCs and progenitors, as they are easily accessible, non-invasive, and universally available. We generated human induced pluripotent stem cells (hiPSCs) from the urinary cells of a healthy donor using a Sendai virus-based gene delivery method. Th...

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Bibliographic Details
Main Authors: Kyung-Ok Uhm, Eun Hee Jo, Gue Youn Go, So-Jung Kim, Hye Young Choi, Young Sam Im, Hye-Yeong Ha, Ji-Won Jung, Soo Kyung Koo
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117300636
Description
Summary:Urinary cells can be an ideal source for generating hiPSCs and progenitors, as they are easily accessible, non-invasive, and universally available. We generated human induced pluripotent stem cells (hiPSCs) from the urinary cells of a healthy donor using a Sendai virus-based gene delivery method. The generated hiPSC line, KSCBi001-A, has a normal karyotype (46,XY). The pluripotency and capacity of multilineage differentiation were characterized by comparison with those of a human embryonic stem cell line. This cell line is registered and available from National Stem Cell Bank, Korea National Institute of Health.
ISSN:1873-5061
1876-7753