Efficacy and Safety of Low-Dose Cyclosporine with Everolimus and Steroids in de novo Heart Transplant Patients: A Multicentre, Randomized Trial

Efficacy and Safety of Low-Dose Cyclosporine with Everolimus and Steroids in de novo Heart Transplant Patients: A Multicentre, Randomized Trial

A six-month, multicenter, randomized, open-label study was undertaken to determine whether renal function is improved using reduced-exposure cyclosporine (CsA) versus standard-exposure CsA in 199 de novo heart transplant patients receiving everolimus and steroids ± induction therapy. Mean C2 levels...

Full description

Bibliographic Details
Main Authors:	Andreas Zuckermann, Shoei-Shen Wang, Heather Ross, Maria Frigerio, Howard J. Eisen, Christoph Bara, Daniel Hoefer, Maurizio Cotrufo, Gaohong Dong, Guido Junge, Anne M. Keogh
Format:	Article
Language:	English
Published:	Hindawi Limited 2011-01-01
Series:	Journal of Transplantation
Online Access:	http://dx.doi.org/10.1155/2011/535983

Similar Items

Everolimus with low-dose cyclosporine in de novo renal transplant recipients: A single center Indian experience
by: Sailaja Kesiraju, et al.
Published: (2015-01-01)

Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat.
by: Rahul Bohra, et al.
Published: (2012-01-01)

Utilization of Mycophenolic Acid, Azathioprine, Tacrolimus, Cyclosporin, Sirolimus, and Everolimus: Multinational Study
by: Majda Sahman, et al.
Published: (2021-03-01)

The role of everolimus in liver transplantation
by: Ganschow R, et al.
Published: (2014-09-01)

Cyclosporine A and steroid therapy in childhood steroid-resistant nephrotic syndrome
by: Gargah Tahar, et al.
Published: (2010-08-01)

EVEROLIMUS IN DE NOVO RENAL TRANSPLANT RECIPIENTS
by: E. I. Prokopenko
Published: (2010-06-01)

Everolimus and Malignancy after Solid Organ Transplantation: A Clinical Update
by: Hallvard Holdaas, et al.
Published: (2016-01-01)

Simultaneous Determination of Cyclosporine A, Tacrolimus, Sirolimus, and Everolimus in Whole-Blood Samples by LC-MS/MS
by: Mustafa Karapirli, et al.
Published: (2012-01-01)

Cyclosporine therapy in steroid-dependent or steroid-resistant idiopathic focal and segmental glomerulosclerosis
by: Imen Gorsane, et al.
Published: (2016-01-01)

Efficiency and safety of the everolimus in patients with the generalized renal cell carcinoma (multicentral observational study)
by: M. I. Volkova, et al.
Published: (2016-06-01)

TREATMENT OF STEROID DEPENDENT ASTHMATICS WITH LOW DOSES OF CYCLOSPORINE
by: Stanislav Šuškovič, et al.
Published: (2004-01-01)

Cyclosporin-A Treatment in Steroid Nonresponsive Nephrotic Syndrome
by: IGN Wila Wirya, et al.
Published: (2018-11-01)

Treatment of Steroid and Cyclosporine-Resistant Idiopathic Nephrotic Syndrome in Children
by: A. A. Nikibakhsh, et al.
Published: (2011-01-01)

Onset and progression of diabetes in kidney transplant patients receiving everolimus or cyclosporine therapy: an analysis of two randomized, multicenter trials
by: Claudia Sommerer, et al.
Published: (2018-09-01)

Everolimus in Heart Transplantation: An Update
by: Stephan W. Hirt, et al.
Published: (2013-01-01)

Colectomy rate in steroid-refractory colitis initially responsive to cyclosporin: a long-term retrospective cohort study
by: David Ezio, et al.
Published: (2007-03-01)

Everolimus &ndash; a new approach in the treatment of renal cell carcinoma
by: G Anandappa, et al.
Published: (2010-03-01)

Drug interactions and metabolism of cyclosporin A and steroids by human liver microsomes in vitro
by: Abu-Omar, Ghada M.
Published: (1992)

Histological findings to five years after early conversion of kidney transplant patients from cyclosporine to everolimus: an analysis from the randomized ZEUS study
by: Ute Eisenberger, et al.
Published: (2018-06-01)

Vorolanib and everolimus: Lenvatinib and everolimus part deux, or something new?
by: Alexander Chehrazi-Raffle, et al.
Published: (2020-06-01)

Do Palliative Steroids Prolong Survival in Dogs With Multicentric Lymphoma?
by: Clare M Knottenbelt
Published: (2018-02-01)

Recommendations for the use of everolimus in de novo kidney transplantation: False beliefs, myths and realities
by: Julio Pascual, et al.
Published: (2017-05-01)

Invasive haemodynamics in de novo everolimus vs. calcineurin inhibitor heart transplant recipients
by: Niklas Bergh, et al.
Published: (2020-04-01)

Long-term treatment of childhood refractory and steroid dependent nephrotic syndrome with Cyclosporin A
by: Madani A, et al.
Published: (2002-07-01)

Everolimus in kidney transplantation
by: Cooper JE, et al.
Published: (2011-07-01)

Efficacy and safety of cyclosporine a for patients with steroid-resistant nephrotic syndrome: a meta-analysis
by: Hong-Yan Li, et al.
Published: (2019-10-01)

Successful cyclosporin and ustekinumab combination therapy in a patient with severe steroid-refractory ulcerative colitis
by: Ingo Ganzleben, et al.
Published: (2020-10-01)

Validation of a simple liquid chromatography coupled to tandem mass spectrometry method for the simultaneous determination of tacrolimus, sirolimus, everolimus and cyclosporin A in dried matrix on paper discs
by: Ignacio Guillermo Bressán, et al.
Published: (2021-01-01)

Pharmacoeconomic analysis of everolimus immunosuppressive therapy for <i>de novo</i> kidney transplant recipients in Russia
by: N. A. Avxentyev, et al.
Published: (2019-05-01)

Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy
by: Saito Mayu, et al.
Published: (2019-01-01)

Efficacy and safety of cyclosporine versus tacrolimus in steroid and cyclophosphamide resistant nephrotic syndrome: A prospective study
by: N Prasad, et al.
Published: (2018-01-01)

Everolimus in Erdheim-Chester disease
by: Mohamed A. Hussein, et al.
Published: (2013-01-01)

Everolimus-eluting coronary stents
by: Alejandro Saez, et al.
Published: (2010-09-01)

ELEVATE: an innovative study design to assess the efficacy, safety, and evolution of cardiovascular parameters in de novo kidney transplant recipients after early conversion from a calcineurin inhibitor to everolimus
by: van der Giet M, et al.
Published: (2014-03-01)

Three-Year Outcomes in Kidney Transplant Patients Randomized to Steroid-Free Immunosuppression or Steroid Withdrawal, with Enteric-Coated Mycophenolate Sodium and Cyclosporine: The Infinity Study
by: A. Thierry, et al.
Published: (2014-01-01)

Combination of Everolimus with Sorafenib for Solid Renal Tumors in Tsc2+/− Mice Is Superior to Everolimus Alone
by: Jian Yang, et al.
Published: (2017-02-01)

Patterns of conjunctival and scleral regeneration after intraoperative application of cyclosporin A solution in rabbits with steroid-induced glaucoma
by: T. A. Zhigalskiaya, et al.
Published: (2021-07-01)

Comparative Evaluation of Tacrolimus and Cyclosporine in Patients with Steroid-resistant Nephrotic Syndrome: A Systematic Review and Meta-analysis
by: Yalda Ravanshad, et al.
Published: (2019-09-01)

Efficacy, Safety and Steroid-sparing Effect of Topical Cyclosporine A 0.05% for Vernal Keratoconjunctivitis in Indian Children
by: Arkendu Chatterjee, et al.
Published: (2019-10-01)

Biological activity of cyclosporin A and cyclosporin G metabolites
by: Copeland, Kenneth Robert.
Published: (2013)

Cannot write session to /tmp/vufind_sessions/sess_fiouc92pimlsn89c8aibmupbp3