Age-Related Changes in Insulin-like Signaling Lead to Intermediate-Term Memory Impairment in Drosophila

Insulin and insulin-growth-factor-like signaling (IIS) plays important roles in the regulation of development, growth, metabolic homeostasis, and aging, as well as in brain functions such as learning and memory. The temporal-spatial role of IIS in learning and memory and its effect on age-dependent...

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Bibliographic Details
Main Authors: Kento Tanabe, Motoyuki Itoh, Ayako Tonoki
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717301109