NADH oxidase functions as an adhesin in Streptococcus pneumoniae and elicits a protective immune response in mice.

NADH oxidase functions as an adhesin in Streptococcus pneumoniae and elicits a protective immune response in mice.

The initial event in disease caused by S. pneumoniae is adhesion of the bacterium to respiratory epithelial cells, mediated by surface expressed molecules including cell-wall proteins. NADH oxidase (NOX), which reduces free oxygen to water in the cytoplasm, was identified in a non-lectin enriched pn...

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Main Authors: Lena Muchnik, Asad Adawi, Ariel Ohayon, Shahar Dotan, Itai Malka, Shalhevet Azriel, Marilou Shagan, Maxim Portnoi, Daniel Kafka, Hannie Nahmani, Angel Porgador, Jonathan M Gershoni, Donald A Morrison, Andrea Mitchell, Michael Tal, Ronald Ellis, Ron Dagan, Yaffa Mizrachi Nebenzahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620118?pdf=render

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